Extreme Morning Sickness? Scientists Finally Pinpoint A Possible Cause

Researchers have been pinpointing a hormone that was released by rising fetuses that might lead to a debilitating type of sickness. 

Women who are relatively more sensitive to this particular hormone, which increases during the early days of pregnancy, might be at more risk of undergoing a serious form of vomiting and nausea, known as hyperemesis gravidarum, as per their study. 

Tito Borner, a popular physiologist at the University of Pennsylvania, said in this context, “For the first time, hyperemesis gravidarum could be addressed at the root cause, rather than merely alleviating its symptoms.” On 13th December, Nature1 published the work. 

The finding can also open up multiple avenues for treatment purposes. Stephen O’Rahilly, co-author and a metabolism researcher at the United Kingdom’s University of Cambridge, said, “We now have a clear view of what may cause this problem and a route for both treatment and prevention.”

The researchers discovered that women with really high levels of GDF15 hormone before they experienced pregnancy had absolutely minimal reactions to it while carrying their kids. The research suggests that GDF15 impacts the danger of severe illnesses; other factors might also play a role.

Approximately 70% of women experience vomiting and nausea during pregnancy, known as morning sickness, even though it can take place at any particular time. Almost 0.3 to 2% undergo hyperemesis gravidarum – the symptoms are so severe that they might face difficulty doing daily activities, drinking, and eating. 

In the worst cases, this can easily cause death due to dehydration. O’Rahilly even said, “It is extremely disabling.”

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